The effectiveness of cognitive rehabilitation of inhibitory control, transcranial direct current stimulation and combination of inhibitory control and transcranial direct current stimulation on inhibitory control and working memory in children with attention deficit disorder/hyperactivity

Document Type : Original Article

Authors

1 PhD Student in General Psychology, Department of Psychology, Borujerd Branch, Islamic Azad University, Borujerd, Iran

2 Assistant Professor, Department of Psychiatry, School of Medicine, Arak University of Medical Sciences, Arak, Iran

3 Associate Professor, Faculty of Psychology and Educational Sciences, Allameh Tabatabaei University, Tehran, Iran

4 Assistant Professor, Department of Psychology, Faculty of Humanities, Arak University, Arak, Iran.

Abstract

Inhibitory cognitive rehabilitation and Transcranial Direct Current Stimulation can be therapeutic alternatives to stimulant drugs in attention deficit/hyperactivity disorder, and there is evidence of their effectiveness in improving cognitive function and clinical symptoms. The aim of this study was to compare the effectiveness of cognitive rehabilitation of inhibitory control, transcranial direct current stimulation and the combination of inhibitory control rehabilitation and transcranial direct current stimulation on inhibitory control and working memory of children with attention deficit hyperactivity disorder. The method of the present study is quasi-experimental with an unbalanced control group design. The quasi-experimental design of the present study was pre-test-post-test and follow-up (2 months) with the control group. The population included all those with ADHD disorder in Arak in the academic year of 2019-2020. The sample consisted of 60 students in the age range of 8 -12 in Arak who referred to counseling centers and student psychological services and answered the Swanson Attention Deficit Hyperactivity Disorder Questionnaire. The students were assigned to experimental and control groups (15 individuals in each group). To collect the data, Swanson et al.'s Attention Deficit Hyperactivity Disorder Questionnaire, N-Back Kirchner test and Stroop computer test were used. The experimental group received a rescue inhibitory cognitive rehabilitation program, and transcranial direct current stimulation and a combination of these programs over the F4 points. The data were analyzed using SPSS.26 software and mixed covariance analysis with repeated measures. The results showed that inhibitory cognitive rehabilitation, Transcranial Direct Current Stimulation and combination of inhibitory cognitive rehabilitation of Transcranial Direct Current Stimulation are effective on the components of inhibitory control and working memory (p ≥ 0.001). The results of Bonferroni post hoc tests showed that there is a significant difference between inhibitory control and working memory of experimental and control groups (p ≥ 0.01). It can be concluded that inhibitory cognitive rehabilitation, Transcranial Direct Current Stimulation and a combination of the two can be used as a single treatment or along with other psychological therapies for children with ADHD.

Keywords

References

Abedanzade, Rasoul & Albogbeish, Saeid (2018). The effect of transcranial electrical stimulation on selective attention in dual task conditions. Journal of Applied Psychological Research, 8 (3), 10-14.
Ahmed, G.K., Darwish, A.M., Khalifa, H. et al. (2022). Relationship between Attention Deficit Hyperactivity Disorder and epilepsy: a literature review. Egypt J Neurol Psychiatry Neurosurg 58, 52 (2022). doi: 10.1186/s41983-022-00482-w
Ansari, Noureddin Nakhostin; Naghdi, Sofia (2013). Rehabilitation techniques in the treatment of stroke. Tehran: Arjmand.
Åkerlund, E., Esbjörnsson, E., Sunnerhagen, K. S., & Björkdahl, A. (2013). Can computerized working memory training improve impaired working memory, cognition and psychological health? Brain Injury, 27(13-14), 1649-1657.
     doi:10.3109/02699052.2013.830195
Assef, E., Capovilla, A., & Capovilla, F. (2007). Computerized Stroop Test to Assess Selective Attention in Children with Attention Deficit Hyperactivity Disorder. The Spanish Journal of Psychology, 10(1), 33-40. doi:10.1017/s1138741600006296
Barkley, R. A. (2011). Barkley Functional Impairment Scale (BFIS for Adults). New York: Guilford Press.
Barkley, R. A. (2013). Taking charge of ADHD: The complete, authoritative guide for parents, 3rd edition. New York: Guilford Press.
Barkley, R.A. (2011) Barkley deficits in executive functioning scale (BDEFS). Guilford Press, New York.
Barlett, C. P., Vowels, C. I., Shanteau, J., Crow, J., & Miller, T. (2009). The effect of violent and non violent computer games on cognitive performance: computers and human behavior, 25, 96.102. doi:10.1016/j.chb.2008.07.008
Bennett, R. (2018). The Relationship between Attention and Emotion Regulation in Attention Deficit/Hyperactivity Disorder. Doctoral dissertation, Fordham University.
Breitling, C., Zaehle, T., Dannhauer, M., Bonath, B., Tegelbeckers, J., Flechtner, H. H., & Krauel, K. (2016). Improving interference control in ADHD patients with transcranial direct current stimulation (tDCS). Frontiers in Cellular Neuroscience, 10, 72. doi:10.3389/fncel.2016.00072
Castellanos, I., Kronenberger, W. G., & Pisoni, D. B. (2018). Questionnaire-based assessment of executive functioning: Psychometrics. Applied Neuropsychology: Child, 7(2), 93-109.
     doi:10.1080/21622965.2016.1248557
Chambers, S. A. (2016). Short-burst-high-intensity exercise to improve working memory in preadolescent children diagnosed with attention deficit hyperactivity disorder, Doctoral dissertation, Piedmont College.
Chase, H. W., Boudewyn, M. A., Carter, C. S., & Phillips, M. L. (2020). Transcranial direct current stimulation: a roadmap for research, from mechanism of action to clinical implementation. Molecular psychiatry, 25(2), 397–407. doi: 10.1038/s41380-019-0499-9
Chen, Y.N., Mitra S., & Schlaghecken, F. (2008). Subprocesses of Working Memory in the N-back Task: An Investigation Using ERPs. Clinical Neurophysiology, 119(5), 1546-1559. doi:10.1016/j.clinph.2008.03.003
Clark, V. P., Coffman, B. A., Trumbo, M. C., & Gasparovic, C. (2011). Transcranial direct current stimulation (tDCS) produces localized and specific alterations in neurochemistry: a 1H magnetic resonance spectroscopy study. Neuroscience letters. 500(1), 67-71. doi: 10.1016/j.neulet.2011.05.244
D’Urso, G., Dell’Osso, B., Rossi, R., Brunoni, A. R., Bortolomasi. M., Ferrucci, R. et al. (2017). Clinical predictors of acute response to transcranial direct current stimulation (tDCS) in major depression. Journal Affect Disorder,  219, 25–30. doi: 10.1016/j.jad.2017.05.019
Doebel, S. (2020). Rethinking Executive Function and its Development. Perspectives on Psychological Science, doi: 10.1177%2F1745691620904771
Elia, J., Arcos-Burgos, M., Bolton, K. L., Ambrosini, P. J., Berrettini, W., & Muenke, M. (2009). ADHD latent class clusters: DSM-IV subtypes and comorbidity. Psychiatry Research, 170, 192–198. doi: 10.1016/j.psychres.2008.10.008
Golden, C. J. (1978). Stroop Color and Word Test: A Manual for Clinical and Experimental Uses. Chicago, IL: Stoelting Co.
Guse, B., Falkai, P., & Wobrock, T., (2010). Cognitive effects of high-frequency repetitive transcranial magnetic stimulation: a systematic review. J. Neural Transm. 117(1), 105-122.
      doi:10.1007/s00702-009-0333-7
Harrison, B. J., Shaw, M., Yucel, M., Purcell, R., Brewer, W. J., Strother, S. C., Egan, G. F., Olver, J. S., Nathan, P. J., & Pantelis, C. (2005). Functional connectivity during Stroop task performance. Neuroimage. 24(1), 181-191.
      doi:10.1016/j.neuroimage.2004.08.033
Hobson, C. W., Scott, S., & Rubia, K. (2011). Investigation of Cool and Hot Executive Function in ODD/CD Independently of ADHD. Journal Child Psychology and Psychiatry. 52(18), 1035-43. doi:10.1111/j.1469-7610.2011.02454.x
Jahangiri, D., Alizadeh, H., Pazeshk, S. H., Farokhi, N. A. (2021). [Effect of a Positive Discipline Parent Education Program on Executive Functions of Children With Attention Deficit Hyperactivity Disorder (Persian)]. Scientific Journal of Rehabilitation Medicine, 10(2), 246-257. doi:10.22037/jrm.2020.112877.2277
Kiani, Behnaz & Hadianfar, Habib (2015). Psychometric Properties of the Persian Form of Self-Reporting Swanson, Nolan and Pelham Grading Scale (Fourth Edition) for screening attention deficit / hyperactivity disorder in adolescents. Iranian Journal of Psychiatry and Clinical Psychology (Thought and Behavior), 21 (4), 317-326. doi:10.1177%2F1087054717738084
Khayyer, Z., Nejati V., & Fathabadi, J. (2014). The effect of induced stress on the number of mistakes in Visual Working Memory for Emotional & none emotional stimuli. Knowledge & Research in Applied Psychology, 15(58), 88-101. [Persian]
Kim, S. H., Han, H. J., Ahn, H. M., Kim, S. A., & Kim, S. E. (2012). Effects of five daily high-frequency rTMS on Stroop task performance in aging individuals. Neuroscience Research. 74(3), 256-260. doi:10.1016/j.neures.2012.08.008
Kirchner, W.K. (1958). Age differences in short-term retention of rapidly changing information. Journal of Experimental Psychology, 55(4), 352–358. doi:10.1037/h0043688
Klingberg, T. (2010). Training and plasticity of working memory. Trends in cognitive sciences, 14(7), 317-324. doi:10.1016/j.tics.2010.05.002
Kolb, Bryan. & Whishaw, Ian.Q (2016). Fundamentals of human neurosycology. Translated by Ahmad Alipour, Mojgan Agah Harris, Abdolreza Mansouri Rad, Ataollah Mohammadi (2015), Tehran: Arjmand Publications.
Lambez, B., Harwood-Gross, A., Golumbic, E. Z., & Rassovsky, Y. (2020). Nonpharmacological interventions for cognitive difficulties in ADHD: A systematic review and meta-analysis. Journal of psychiatric research, 120(1), 40-55. doi:10.1016/j.jpsychires.2019.10.007
Larsson, H., Dilshad, R., Lichtenstein, P., & Barker, E. D. (2011). Developmental trajectories of DSM‐IV symptoms of attention‐ deficit/hyperactivity disorder: Genetic effects, family risk and associated psychopathology. Journal of Child Psychology and Psychiatry, 52(9), 954-963.
     doi:10.1111/j.1469-7610.2011.02379.x
Lipka, R., Ahlers, E., Reed, T. L., Karstens, M. I., Nguyen, V., Bajbouj, M., Kadosh, R. C. (2021). Resolving heterogeneity in transcranial electrical stimulation efficacy for attention deficit hyperactivity disorder. Experimental Neurology, 37, 113586. doi:10.1016/j.expneurol.2020.113586
Luo, Y., Weibman, D., Halperin, J., & Li, X. (2019). A Review of Heterogeneity in Attention Deficit/Hyperactivity Disorder (ADHD). Frontiers in human neuroscience, 13, 42. doi:10.3389/fnhum.2019.00042
Madani, Seyed Samira; Alizadeh, Hamid; Farrokhi, Noor Ali & Hakimi Rad, Elham (2017). Development of a training program for executive functions (response inhibition, updating, sustained attention) and evaluate its effectiveness in reducing the symptoms of children with attention deficit / hyperactivity disorder. Psychology of Exceptional People, 7 (26), 1-25. doi:10.22054/jpe.2017.24627.1622
Maoz, H., Gvirts, H. Z., Sheffer, M., & Bloch, Y. (2019). Theory of Mind and empathy in children with ADHD. Journal of Attention Disorders, 23(11), 1331-1338. doi:10.1177/1087054717710766
Mueller, A. K., Tucha, L., Koerts, J., Groen, Y., Lange, K. W., & Tucha, O. (2014). Sluggish cognitive tempo and its neurocognitive, social and emotive correlates: a systematic review of the current literature. Journal of Molecular Psychiatry, 2(1), 5. doi:10.1186/2049-9256-2-5
Müller, A., Vetsch, S., Pershin, I., Candrian, G., Baschera, G. M., Kropotov, J. D., & Eich, D. (2019). EEG/ERP-based biomarker/neuroalgorithms in adults with ADHD: Development, reliability, and application in clinical practice. The World Journal of Biological Psychiatry, 1-11. doi:10.1080/15622975.2019.1605198
Nejati, V. (2020). Cognitive rehabilitation in children with attention deficit- hyperactivity disorder: Transferability to untrained cognitive domains and behavior. Asian Journal of Psychiatry, 49, 101949. doi:10.1016/j.ajp.2020.101949
Olesen, P. J., Westerberg, H., & Klingberg, T. (2004). Increased prefrontal and parietal activity after training of working memory. Nature neuroscience, 7(1), 75. doi:10.1038/nn1165
Owen, A.M., Hampshire, A., & Grahn, J.A. (2010). putting brain training to the test nature. Europe PMC Funders Group, 465(7299), 775-778. doi:10.1038/nature09042
Pilli, R., Naidu, M., Pingali, U. R., Shobha, J. C., & Reddy, A. P. (2013). A computerized stroop test for the evaluation of psychotropic drugs in healthy participants. Indian journal of psychological medicine, 35(2), 180–189.doi:10.4103/0253-7176.116251
Plewnia, C., Zwissler, B., Längst, I ,.Maurer, B., Giel, K., & Krüger, R. (2013). Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism. Cortex, 49(7), 1801-1807. doi:10.1016/j.cortex.2012.11.002
Poon, K. (2018). Hot and Cool Executive Functions in Adolescence: Development and Contributions to Important Developmental Outcomes. Front Psychol. 8(2), 11-23. doi:10.3389/fpsyg.2017.02311
Renou, S., & Doyen, C. (2019). Programme de Remédiation cognitive NEAR (Neuropsychological Educational Approach to Cognitive Remediation) chez des adolescents présentant un Trouble Déficit de l’Attention/Hyperactivité et/ou un Trouble du spectre Autistique. Annales Médico-psychologiques, revue psychiatrique. doi:10.1016/J.AMP.2018.07.012
Roselló, B., Berenguer, C., Baixauli, I., Mira, Á., Martinez-Raga, J., & Miranda, A. (2020). Empirical examination of executive functioning, ADHD associated behaviors, and functional impairments in adults with persistent ADHD, remittent ADHD, and without ADHD. BMC psychiatry, 20(1), 134. doi:10.1186/s12888-020-02542-y.
Rubia, K., Westwood, S., Aggensteiner, P. M., & Brandeis, D. (2021). Neurotherapeutics for Attention Deficit/Hyperactivity Disorder (ADHD): A Review. Cells, 10(8), 2156. doi:10.3390/cells10082156.
Ruf, S. P., Fallgatter, A. J., Plewnia, C. (2017). Augmentation of working memory training by transcranial direct current stimulation (tDCS). Scientific Reports, 7, 876.
     doi:10.1038/s41598-017-01055-1
Salehinejad, M. A., Nejati, V., Mosayebi-Samani, M., Mohammadi, A., Wischnewski, M., Kuo, M. F., Avenanti, A., Vicario, C. M., & Nitsche, M. A. (2020). Transcranial Direct Current Stimulation in ADHD: A Systematic Review of Efficacy, Safety, and Protocol-induced Electrical Field Modeling Results. Neuroscience bulletin, 36(10), 1191–1212. doi:10.1007/s12264-020-00501-x.
Shahwan, M., Suliman, A., Jairoun, A., et al. (2020). Attention deficit hyperactivity disorder: Knowledge and perception of dental care providers at Ajman. Journal of Pharmacy and Bioallied Sciences, 12(1), 16. doi:10.4103%2Fjpbs.JPBS_119_19
Shaw, P., Stringaris, A., Nigg, J., & Leibenluft, E. (2014). Emotion dysregulation in attention deficit hyperactivity disorder. The American journal of psychiatry, 171(3), 276–293. doi:10.1176/appi.ajp.2013.13070966
Soltaninejad, Mansour & Arabzadeh, Abuzar (2018). Investigating the relationship between performance in Stroop test with emotional regulation and academic achievement of students in Mashhad. Recent Advances in Psychology, 46 (21), 83-92.
Stagg, C. J., and Nitsche, M. A. (2011). Physiological basis of transcranial direct current stimulation. Neuroscientist 17, 37–53.
      doi: 10.1177/10738584103 86614.
Swanson, J. M., Kraemer, H. C., Hinshaw, S. P., Arnold, L. E., Conners, C. K., Abikoff, H. B., et al. (2001). Clinical relevance of the primary findings of the MTA: success rates based on severity of ADHD and ODD symptoms at the end of treatment. Journal of the American Academy of Child and Adolescent Psychiatry, 40,168–179.
      doi:10.1097/00004583-200102000-00011
Tajik-Parvinchi, D.J., Wright, L., & Schachar, R.J. (2014). Cognitive Rehabilitation for Attention Deficit/Hyperactivity Disorder (ADHD): Promises and Problems. Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent, 23 3, 207-17 .
Tarle, S. J., Alderson, R. M., Arrington, E. F., Roberts, D. K. (2021). Emotion Regulation and Children With Attention-Deficit/Hyperactivity Disorder: The Effect of Varying Phonological Working Memory Demands. J Atten Disord. 25(6), 851-864. doi:10.1177%2F1087054719864636
Van Leeuwen, M., Van den Berg, S.M., Hoekstra, R.A., & Boomsma, D.I. (2007). Endophenotypes for intelligence in children and adolescents. Intelligence, 35(4), 369-80.
Vanderhasselt, M. A., De Raedt, R., & Baeken, C., (2009). Dorsolateral prefrontal cortex and Stroop performance: tackling the lateralization. Psychon. Bull. Rev. 16(3), 609-612. doi:10.3758/pbr.16.3.609
Westwood, S. J., Radua, J., & Rubia, K. (2021). Noninvasive brain stimulation in children and adults with attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. Journal of psychiatry & neuroscience: JPN, 46(1), E14–E33. doi:10.1503/jpn.190179.
Wilcox, J. (2017). ADHD in Elementary School Students: Impact of Physical Activity on ADHD Symptoms. Master’s Thesis, Minnesota State University, Mankato.
Journal of Research in Psychopathology
Volume 3, Issue 10
2022
Pages 35-47

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